Open Access
LogoLogo
About JournalArchiveSearchFor AuthorsFor ReviewersHelpOnline-Submission
Archive
Vol.48, No.6, 2014
Current Issue
Archive (2009~
Archive-the Korean Journal of Pathology(1967~2008)
Archive-the Korean Journal of Cytopathology(1990~2008)
Most Read Articles
  Vol.21, No.3:138-143, September 1987
Immunohistochemical Demonstration of Fibronectin in Paraquat-Induced Interstitial Fibrosis of Adult Human Lung

Hong Seung-Pyo, Lee Sang-Sook, Chung Chai-Hong

Department of Pathology, Keimyung University School of Medicine, Taegu 700-310, Korea

We studied distribution of fibronectin in paraquat-induced adult fibrotic lung by indirect immunofluorescence and indirect immunoperoxidase methods, using affinity-purified antifibronectin IgG peroxidase conjugates and antifibronectin IgG FITC conjugates. In contrast to the relative paucity of staining in normal lung, there was a marked increase in interstitial staining for fibronectin in this fibrotic lung. This marked alterations in the apparent amounts and distribution of fibronectin in fibrotic human lung suggest its involvement in the cellular events accompanying human lung fibrosis.
Key Words :

Copyright(c) 2008 By the Korean Society of Pathologists & the Korean Society for Cytopathology
Room 1209 Gwanghwamun Officia, 163 Sinmunno 1-ga, Jongno-gu, Seoul 110-999, Korea
Tel: +82-2-795-3094, Fax: +82-2-790-6635, E-mail: jptm@kams.or.kr.
#406 Lilla Swami Bldg, 391-18, Yangjae-dong, Seocho-gu, Seoul 137-130, Korea
Tel: +82-2-593-6943 Fax: +82-2-593-6944, E-mail: cytopathology@hanmail.net