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Vol.48, No.6, 2014
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Archive-the Korean Journal of Pathology(1967~2008)
Archive-the Korean Journal of Cytopathology(1990~2008)
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  Vol.9, No.1:71-76, March 1975
Results of Blood Cultures done over a 5 year Period at Yonsei Medical Center

Yunsop Chong, Hye Sook Kim

Department of Clinical Pathology, Yonsei University College of Medicine, Seoul, Korea

Bacteremia develops during some infections and various bacteria. including opportunistic pathogens, are usually involved. Blood cultures aid etiologic diagnosis and guide treatment by determining antibiotic susceptibility of isolates. Lately, the most frequently isolated organisms are known to be grain-negative bacilli, staphylococci and enterococci, while frequent isolates during the preantibiotic era were well known pathogens such as beta-hemolytic streptococcus, pneumococcus and meningococcus. In this study, laboratory data on blood cultures the years 1969-1973 at Severance hospital were analyzed to determine trends of bacteria isolation. During the 5-year period, 9705 blood cultures from an undetermined number of patients were made and 1,194 positive cultures (799 patients) were obtained. 1. Frequently isolated bacteria in decreasing order were Sal. typhi, Enterobacteriaceae, S.aureus, P. aeruginosa, alpha-hemolytic streptococcus, and enterococcus. 2. Ratio of annual isolation of Enterobacteriaceae to total positive cultures showed a tendency of the organism to increase. 3. Frequently isolated bacteria from pediatric patients were Enterobacteriaceae and S. aureus. In Patients in the 6-49 age group, Sal. typhi was most frequently found and in patients of 50 years and over, it was Enterobacteriaceae. 4. Monthly isolation rate of Sal. typhi showed two peaks; one in June-July and another in November. 5. Polymicrobial bacteremia were found in 2.4% of patients with positive blood cultures. Most of the organisms concerned were those belonging to Enterobacteriaceae. 6. None of the Sal. typhi tested were resistant to chloramphenicol or to ampicillin with Kirby-Bauer disc diffusion method. Many of the isolates of S.aureus and Enerobacteriaceae were resistant to the routinely tested antibiotics.
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